ABCB1 p.Phe343Met
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PMID: 9261097
[PubMed]
Loo TW et al: "Drug-stimulated ATPase activity of human P-glycoprotein requires movement between transmembrane segments 6 and 12."
No.
Sentence
Comment
91
The paired residues Phe-336/Ser-979, Leu-339/Val-982, Phe-343/Met-986, Gly-346/Gly-989, and Pro-350/Ser993 predicted to be close to each other (C, shaded circles) were replaced with cysteine and the mutant P-glycoproteins expressed in HEK 293 cells.
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ABCB1 p.Phe343Met 9261097:91:54
status: NEW