ABCB1 p.Phe336Ser
[switch to full view]Comments [show]
None has been submitted yet.
PMID: 9261097
[PubMed]
Loo TW et al: "Drug-stimulated ATPase activity of human P-glycoprotein requires movement between transmembrane segments 6 and 12."
No.
Sentence
Comment
91
The paired residues Phe-336/Ser-979, Leu-339/Val-982, Phe-343/Met-986, Gly-346/Gly-989, and Pro-350/Ser993 predicted to be close to each other (C, shaded circles) were replaced with cysteine and the mutant P-glycoproteins expressed in HEK 293 cells.
X
ABCB1 p.Phe336Ser 9261097:91:20
status: NEW