ABCB1 p.Met949Cys

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PMID: 8910331 [PubMed] Loo TW et al: "Inhibition of oxidative cross-linking between engineered cysteine residues at positions 332 in predicted transmembrane segments (TM) 6 and 975 in predicted TM12 of human P-glycoprotein by drug substrates."
No. Sentence Comment
138 Each residue at equivalent positions in predicted TM6 (residues Leu-332-Val-338) and TM11 (residues Met-949-Cys-956) was systematically changed to cysteine followed by treatment of the protein with oxidant.
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ABCB1 p.Met949Cys 8910331:138:100
status: NEW
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