ABCB1 p.Phe978Tyr
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PMID: 8104183
[PubMed]
Loo TW et al: "Functional consequences of phenylalanine mutations in the predicted transmembrane domain of P-glycoprotein."
No.
Sentence
Comment
126
Mutants with changes of Phe-978 to Ser, Leu, or Tyr all retained the ability to confer resistance to vinblastine, since drug-resistantcolonies were obtained after transfection with the corresponding mutant cDNAs.
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ABCB1 p.Phe978Tyr 8104183:126:24
status: NEW