ABCB1 p.Trp232*
[switch to full view]Comments [show]
None has been submitted yet.
PMID: 21182301
[PubMed]
Loo TW et al: "The W232R suppressor mutation promotes maturation of a truncation mutant lacking both nucleotide-binding domains and restores interdomain assembly and activity of P-glycoprotein processing mutants."
No.
Sentence
Comment
211
The pattern of rescue of the G251V/W232X mutants was consistent with the prediction that hydrogen bond interactions were responsible for the increase in maturation efficiency.
X
ABCB1 p.Trp232* 21182301:211:35
status: NEW226 (B) The amount of mature P-gp (percent mature) relative to total P-gp (170 plus 150 kDa) in mutant G251V/W232X (X = W, R, D, N, S, Y, A, G, I, or F) is shown.
X
ABCB1 p.Trp232* 21182301:226:105
status: NEW