ABCB1 p.Trp136Arg
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PMID: 21182301
[PubMed]
Loo TW et al: "The W232R suppressor mutation promotes maturation of a truncation mutant lacking both nucleotide-binding domains and restores interdomain assembly and activity of P-glycoprotein processing mutants."
No.
Sentence
Comment
138
The W136R mutation inhibited maturation of G251V as shown previously (42), and the mutant was included in this study as a control (Figure 2B, lanes 8 and 9).
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ABCB1 p.Trp136Arg 21182301:138:4
status: NEW147 The effect of the W136R, W212R, W315R, W708R, and W855R mutations on maturation of wild-type P-gp was then tested.
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ABCB1 p.Trp136Arg 21182301:147:18
status: NEW