ABCB1 p.Trp315Arg

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PMID: 21182301 [PubMed] Loo TW et al: "The W232R suppressor mutation promotes maturation of a truncation mutant lacking both nucleotide-binding domains and restores interdomain assembly and activity of P-glycoprotein processing mutants."
No. Sentence Comment
137 Accordingly, mutants G251V/W212R(TM3), G251V/W315R- (TM5), G251V/W708R(TM7), and G251V/W855R(TM10) were constructed.
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ABCB1 p.Trp315Arg 21182301:137:45
status: NEW
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147 The effect of the W136R, W212R, W315R, W708R, and W855R mutations on maturation of wild-type P-gp was then tested.
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ABCB1 p.Trp315Arg 21182301:147:32
status: NEW
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