ABCB1 p.Tyr42Ala
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PMID: 14622130
[PubMed]
Jodoin J et al: "P-glycoprotein in blood-brain barrier endothelial cells: interaction and oligomerization with caveolins."
No.
Sentence
Comment
75
The MDR1 codons for Tyr42 and Trp45 were replaced with Ala codons by Quikchange protocol (Stratagene, La Jolla, CA, USA) using the primer 5'-TCAATGTTTCGCGCTTCGAATGCGCTTGACAAGT- TG-3' and a primer with the reverse complement sequence.
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ABCB1 p.Tyr42Ala 14622130:75:20
status: NEW207 In the first P-gp mutant, Tyr42 and Trp45 were replaced with Ala residues (YWAA-MDR1).
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ABCB1 p.Tyr42Ala 14622130:207:26
status: NEW