ABCC7 p.Leu211Cys
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PMID: 9724537
[PubMed]
Akabas MH et al: "Channel-lining residues in the M3 membrane-spanning segment of the cystic fibrosis transmembrane conductance regulator."
No.
Sentence
Comment
97
All of the mutants expressed cAMP-activated currents in FIGURE 2: MTS reagents do not inhibit currents induced by wild-type CFTR but they do inhibit currents induced by the L211C mutant.
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ABCC7 p.Leu211Cys 9724537:97:173
status: NEW98 Normalized current at -100 mV recorded from individual oocytes expressing wild-type CFTR (A and C) and the L211C mutant (B and D).
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ABCC7 p.Leu211Cys 9724537:98:107
status: NEW113 In contrast, a 1-min application of 10 mM MTSES- significantly inhibited the CFTR-induced currents for the mutants H199C, F200C, W202C, I203C, P205C, Q207C, and L211C (Figure 4).
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ABCC7 p.Leu211Cys 9724537:113:161
status: NEW