ABCC7 p.Ile1139Cys

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PMID: 21796338 [PubMed] Qian F et al: "Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant."
No. Sentence Comment
90 A similar lack of effect following prolonged (>5 min) exposure to such high concentrations of both MTSES and MTSET was also observed in ten out of 19 cysteine-substituted mutants tested (I1131C, I1132C, L1133C, T1134C, L1135C, A1136C, M1137C, I1139C, L1143C, and A1146C).
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ABCC7 p.Ile1139Cys 21796338:90:243
status: NEW
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PMID: 22042986 [PubMed] Bai Y et al: "Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7)."
No. Sentence Comment
118 (B) Representative current recording of cysless/ I1139C-CFTR channels using a similar experimental protocol as in A.
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ABCC7 p.Ile1139Cys 22042986:118:49
status: NEW
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