ABCC7 p.Trp401Ala
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PMID: 21419343
[PubMed]
Khushoo A et al: "Ligand-driven vectorial folding of ribosome-bound human CFTR NBD1."
No.
Sentence
Comment
114
In addition, mutations that inhibit ATP binding to NBD1 in full-length CFTR (W401A, A462F, and K464A [Berger et al., 2005]) also inhibited binding to truncated NBD1 (Figures 5E and 5F).
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ABCC7 p.Trp401Ala 21419343:114:77
status: NEW205 The CFP-NBD1 ATP-binding mutant contained W401A, A462F, and K464A mutations in the ATP-binding site as predicted by the crystal structure (2BBO).
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ABCC7 p.Trp401Ala 21419343:205:42
status: NEW