ABCC7 p.His775Ala

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PMID: 20952391 [PubMed] Wang G et al: "State-dependent regulation of cystic fibrosis transmembrane conductance regulator (CFTR) gating by a high affinity Fe3+ bridge between the regulatory domain and cytoplasmic loop 3."
No. Sentence Comment
138 Further investigations indicate that only H775A suppressed inhibition by Fe3ϩ and activity of the H775A mutant was also further potentiated by curcumin (data not shown).
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ABCC7 p.His775Ala 20952391:138:42
status: NEW
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ABCC7 p.His775Ala 20952391:138:104
status: NEW
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185 In contrast, the open probability and the single channel conductance were a little higher for the H775A mutant than for the WT channel (Fig. 7C).
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ABCC7 p.His775Ala 20952391:185:98
status: NEW
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247 B and D, open state probability (Po) for the WT hCFTR (B) and the H775A mutant (D) (n ϭ 3-5).
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ABCC7 p.His775Ala 20952391:247:66
status: NEW
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