ABCC7 p.Ser1347Thr
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PMID: 20421370
[PubMed]
Tsai MF et al: "Stable ATP binding mediated by a partial NBD dimer of the CFTR chloride channel."
No.
Sentence
Comment
145
In brief, compared with 2.75 mM ATP, 8-N3-ATP at a saturating concentration (100 µM) catalyzes the opening of WT-CFTR at an approximately two- to threefold slower rate but induces openings approximately fourfold longer, resulting in a maximal Po for channels mutation, such as S1347T (Fig. 5 B).
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ABCC7 p.Ser1347Thr 20421370:145:290
status: NEW