ABCC7 p.Ser909Cys
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PMID: 18658148
[PubMed]
He L et al: "Multiple membrane-cytoplasmic domain contacts in the cystic fibrosis transmembrane conductance regulator (CFTR) mediate regulation of channel gating."
No.
Sentence
Comment
222
In P-glycoprotein, the trapping of AMP-PNP or ADP plus vanadate at NBD reduces the cross-linking of L443C and S909C, suggesting that conformational changes occur at the NBD1/MSD2 interface during the ATP catalytic cycle (33).
X
ABCC7 p.Ser909Cys 18658148:222:110
status: NEW
PMID: 25987565
[PubMed]
Loo TW et al: "The Transmission Interfaces Contribute Asymmetrically to the Assembly and Activity of Human P-glycoprotein."
No.
Sentence
Comment
287
Both mutants L443(NBD1)/S909C(IH4) and A266C(IH2)/ F1086C(NBD2) could be cross-linked with copper phenanthroline but only the L443C/S909C mutant was active.
X
ABCC7 p.Ser909Cys 25987565:287:132
status: NEW