ABCC7 p.Lys114Glu

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PMID: 18449561 [PubMed] Zhou JJ et al: "Identification of positive charges situated at the outer mouth of the CFTR chloride channel pore."
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61 In contrast, K114E, K329E, K892E, and R899E, like wild type, gave almost linear I-V relationships under these conditions.
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ABCC7 p.Lys114Glu 18449561:61:13
status: NEW
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78 The mutations K114E, K329E, K892E, R899E, and R1128E did not affect unitary current amplitude at any voltage (Fig. 4b), consistent with these residues not being involved in Cl- permeation.
X
ABCC7 p.Lys114Glu 18449561:78:14
status: NEW
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