ABCC1 p.Tyr440Ala
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PMID: 18775981
[PubMed]
Grant CE et al: "Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3)."
No.
Sentence
Comment
291
Other conservative (W) and nonconservative (A, E, Q, and S) substitutions of Tyr440 caused significant reductions in LTC4 transport ranging from 75% (Y440Q) to 90% (Y440A and Y440E).
X
ABCC1 p.Tyr440Ala 18775981:291:165
status: NEW