ABCC1 p.Leu3Arg
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PMID: 15252017
[PubMed]
Szentpetery Z et al: "The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers."
No.
Sentence
Comment
185
It was found that the mutants could be expressed in Sf9 insect cells as effectively as the wild type MRP1, and the Leu 3 Arg replacements do not effect the drug-stimulated ATPase activity or the ATP-dependent LTC4 transport activity of the MRP1-variants.
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ABCC1 p.Leu3Arg 15252017:185:115
status: NEW