ABCC1 p.Arg1249Met

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PMID: 12450376 [PubMed] Ren XQ et al: "A positively charged amino acid proximal to the C-terminus of TM17 of MRP1 is indispensable for GSH-dependent binding of substrates and for transport of LTC4."
No. Sentence Comment
229 Membrane vesicles (100 µg of protein) expressing MRP1, MRP1 R1249M, and MRP1 R1222M were photolabeled with [125I]azido AG-A in the absence or presence of the indicated concentrations of GSH as described in the legend ofo Figure 2.
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ABCC1 p.Arg1249Met 12450376:229:65
status: NEW
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