ABCG2 p.Asn590Leu
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PMID: 19949928
[PubMed]
Ross DD et al: "Impact of breast cancer resistance protein on cancer treatment outcomes."
No.
Sentence
Comment
87
found the I206L allele to have high transporter activity but low protein expression when transfected into human embryonic kidney (HEK) cells, whereas the N590L and D620N had higher expression but lower activity (85).
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ABCG2 p.Asn590Leu 19949928:87:154
status: VERIFIED