ABCG2 p.Glu446Asp
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PMID: 14566825
[PubMed]
Miwa M et al: "Single amino acid substitutions in the transmembrane domains of breast cancer resistance protein (BCRP) alter cross resistance patterns in transfectants."
No.
Sentence
Comment
48
Among PA/E446X1 transfectants, PA/E446D expressed a small amount of BCRP. Among PA/R482X2, PA/R482D and PA/R482K expressed lesser amounts of BCRP than the other transfectants.
X
ABCG2 p.Glu446Asp 14566825:48:34
status: VERIFIED112 Such transfectants include PA/E446D, PA/R486D, PA/R486K, PA/N557R, H630K and H630R.
X
ABCG2 p.Glu446Asp 14566825:112:30
status: VERIFIED