ABCG2 p.Ser25Pro
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PMID: 11807788
[PubMed]
Kage K et al: "Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization."
No.
Sentence
Comment
151
to Ala and Tyr-605 to Cys), HABCRP-37 (Thr-82 to Ala) or HABCRP-74 (Ser-25 to Pro, Arg-309 to Gly and Ala-632 to Val), also expressed mutant BCRP protein, but cells transfected with HABCRP-86 (Lys-86 to Ile) did not express BCRP protein and therefore exhibited no drug resistance.
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ABCG2 p.Ser25Pro 11807788:151:68
status: VERIFIED