ABCC1 p.Lys1322Asp
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PMID: 25236767
[PubMed]
Lodwick D et al: "Sulfonylurea receptors regulate the channel pore in ATP-sensitive potassium channels via an intersubunit salt bridge."
No.
Sentence
Comment
90
Single charge reversals in both full-length Kir6.2 and MBP-SUR2-(1294-1358) restored co-immunoprecipitation to at least WT levels from mixtures of Kir6.2-K338E-SUR2- E1318R, Kir6.2-D323K-SUR2-K1322D and Kir6.2-D323K- SUR2-Q1336E (Figures 5e and 5f), indicating that all three of the proposed electrostatic interactions may be important structurally and/or for assembly.
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ABCC1 p.Lys1322Asp 25236767:90:192
status: NEW