ABCC8 p.Thr906Ala
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PMID: 25987565
[PubMed]
Loo TW et al: "The Transmission Interfaces Contribute Asymmetrically to the Assembly and Activity of Human P-glycoprotein."
No.
Sentence
Comment
294
The D164C/D805C mutant could be efficiently rescued when expressed in the presence of cyclosporine A to yield mature P-gp as the major product.
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ABCC8 p.Thr906Ala 25987565:294:54
status: NEW253 We constructed histidine-tagged R262A/R905A and T263A/ T906A mutants (in wild-type background) to test if mutations in both IH2 and IH4 were needed to inactivate P-gp ATPase activity.
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ABCC8 p.Thr906Ala 25987565:253:55
status: NEW